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Retrospective evidence on outcomes and experiences of pregnancy and childbirth in epidermolysis bullosa in Australia and New Zealand()()()
BACKGROUND: Pregnancy in epidermolysis bullosa (EB) has not been comprehensively studied. OBJECTIVE: We aimed to develop a foundational database, which could provide peri-obstetric advice in EB. METHODS: Survey questionnaires were sent to obstetricians, unaffected mothers of EB babies, and mothers w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418959/ https://www.ncbi.nlm.nih.gov/pubmed/28492031 http://dx.doi.org/10.1016/j.ijwd.2017.02.002 |
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author | Intong, Lizbeth R.A. Choi, S. Deanne Shipman, Alexa Kho, Yong C. Hwang, Shelley J.E. Rhodes, Lesley M. Walton, Judie R. Chapman, Michael G. Murrell, Dédée F. |
author_facet | Intong, Lizbeth R.A. Choi, S. Deanne Shipman, Alexa Kho, Yong C. Hwang, Shelley J.E. Rhodes, Lesley M. Walton, Judie R. Chapman, Michael G. Murrell, Dédée F. |
author_sort | Intong, Lizbeth R.A. |
collection | PubMed |
description | BACKGROUND: Pregnancy in epidermolysis bullosa (EB) has not been comprehensively studied. OBJECTIVE: We aimed to develop a foundational database, which could provide peri-obstetric advice in EB. METHODS: Survey questionnaires were sent to obstetricians, unaffected mothers of EB babies, and mothers with EB. Results were analyzed using chi-square, Fisher exact, and t-tests. RESULTS: Out of 1346 obstetricians surveyed, 195 responded, and only 14 had encountered EB. All recommended normal vaginal delivery (NVD), except for one elective Caesarean section (CS). We received responses from 75 unaffected mothers who had delivered EB babies. They had significantly more complications in their EB pregnancies compared to their non-EB pregnancies. A further 44 women with various types of EB who had given birth responded. Most delivered via NVD and had no significant increase in complications in both their EB and non-EB pregnancies. In both groups, there were no significant differences in blistering at birth in babies delivered via NVD and CS. CONCLUSION: In conclusion, most patients with EB who are capable of giving birth do not have an increased risk for pregnancy-related complications and NVD appears to be safe. Awareness of this data amongst obstetricians and dermatologists should lead to improved quality of care for mothers and babies affected with EB. |
format | Online Article Text |
id | pubmed-5418959 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-54189592017-05-10 Retrospective evidence on outcomes and experiences of pregnancy and childbirth in epidermolysis bullosa in Australia and New Zealand()()() Intong, Lizbeth R.A. Choi, S. Deanne Shipman, Alexa Kho, Yong C. Hwang, Shelley J.E. Rhodes, Lesley M. Walton, Judie R. Chapman, Michael G. Murrell, Dédée F. Int J Womens Dermatol Article BACKGROUND: Pregnancy in epidermolysis bullosa (EB) has not been comprehensively studied. OBJECTIVE: We aimed to develop a foundational database, which could provide peri-obstetric advice in EB. METHODS: Survey questionnaires were sent to obstetricians, unaffected mothers of EB babies, and mothers with EB. Results were analyzed using chi-square, Fisher exact, and t-tests. RESULTS: Out of 1346 obstetricians surveyed, 195 responded, and only 14 had encountered EB. All recommended normal vaginal delivery (NVD), except for one elective Caesarean section (CS). We received responses from 75 unaffected mothers who had delivered EB babies. They had significantly more complications in their EB pregnancies compared to their non-EB pregnancies. A further 44 women with various types of EB who had given birth responded. Most delivered via NVD and had no significant increase in complications in both their EB and non-EB pregnancies. In both groups, there were no significant differences in blistering at birth in babies delivered via NVD and CS. CONCLUSION: In conclusion, most patients with EB who are capable of giving birth do not have an increased risk for pregnancy-related complications and NVD appears to be safe. Awareness of this data amongst obstetricians and dermatologists should lead to improved quality of care for mothers and babies affected with EB. Elsevier 2017-02-16 /pmc/articles/PMC5418959/ /pubmed/28492031 http://dx.doi.org/10.1016/j.ijwd.2017.02.002 Text en © 2015 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Intong, Lizbeth R.A. Choi, S. Deanne Shipman, Alexa Kho, Yong C. Hwang, Shelley J.E. Rhodes, Lesley M. Walton, Judie R. Chapman, Michael G. Murrell, Dédée F. Retrospective evidence on outcomes and experiences of pregnancy and childbirth in epidermolysis bullosa in Australia and New Zealand()()() |
title | Retrospective evidence on outcomes and experiences of pregnancy and childbirth in epidermolysis bullosa in Australia and New Zealand()()() |
title_full | Retrospective evidence on outcomes and experiences of pregnancy and childbirth in epidermolysis bullosa in Australia and New Zealand()()() |
title_fullStr | Retrospective evidence on outcomes and experiences of pregnancy and childbirth in epidermolysis bullosa in Australia and New Zealand()()() |
title_full_unstemmed | Retrospective evidence on outcomes and experiences of pregnancy and childbirth in epidermolysis bullosa in Australia and New Zealand()()() |
title_short | Retrospective evidence on outcomes and experiences of pregnancy and childbirth in epidermolysis bullosa in Australia and New Zealand()()() |
title_sort | retrospective evidence on outcomes and experiences of pregnancy and childbirth in epidermolysis bullosa in australia and new zealand()()() |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418959/ https://www.ncbi.nlm.nih.gov/pubmed/28492031 http://dx.doi.org/10.1016/j.ijwd.2017.02.002 |
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