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Intra-individual Right-left Comparative Study of Medium Depth Peels in Superficial Nail Abnormalities

BACKGROUND: Superficial nail abnormalities include conditions which produce nail surface changes such as trachyonychia, pitting and ridging. Mostly, this is a neglected area due to the dearth of treatment options. Glycolic acid peeling has been reported to be effective in such cases. AIM: This study...

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Autores principales: Daulatabad, Deepashree, Nanda, Soni, Grover, Chander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418978/
https://www.ncbi.nlm.nih.gov/pubmed/28529418
http://dx.doi.org/10.4103/0974-2077.204580
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author Daulatabad, Deepashree
Nanda, Soni
Grover, Chander
author_facet Daulatabad, Deepashree
Nanda, Soni
Grover, Chander
author_sort Daulatabad, Deepashree
collection PubMed
description BACKGROUND: Superficial nail abnormalities include conditions which produce nail surface changes such as trachyonychia, pitting and ridging. Mostly, this is a neglected area due to the dearth of treatment options. Glycolic acid peeling has been reported to be effective in such cases. AIM: This study aims to assess the safety and efficacy of medium depth peels (70% glycolic acid versus phenol combination peel [8% phenol with 15% trichloroacetic acid]) in patients with superficial nail abnormalities. MATERIALS AND METHODS: A right-left comparative study in patients with superficial nail abnormalities was done. On the right finger or toenails phenol combination peels and on the left side 70% glycolic acid was used in a predefined protocol over 12 weeks. The severity was assessed objectively by a new devised index (Nail Surface abnormality Index (NSI]). Patient's subjective perception of severity was assessed by Visual Analogue Scale (VAS), and that of the physician was assessed by Physician's Global Assessment (PGA) scores. RESULTS: A total of 17 patients were enrolled, two dropped out and 15 patients were included in the final analysis (mean age 19.2 years, total 120 nails treated). The mean NSI score declined from 7.88 ± 0.45 to 4.02 ± 0.45 on the right side; and from 8.0 ± 0.45 to 4.32 ± 0.44 on left side, at the end of 12 weeks. The VAS declined from 6.57 ± 0.26 to 3.87 ± 0.33 on right side and from 6.32 ± 0.28 to 3.78 ± 0.32 on left side. According to PGA score, five patients showed good improvement, seven showed moderate improvement and three responded poorly. CONCLUSION: Both the medium depth peels were found to be safe and equally efficacious modalities for treatment of superficial nail abnormalities.
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spelling pubmed-54189782017-05-19 Intra-individual Right-left Comparative Study of Medium Depth Peels in Superficial Nail Abnormalities Daulatabad, Deepashree Nanda, Soni Grover, Chander J Cutan Aesthet Surg Original Article BACKGROUND: Superficial nail abnormalities include conditions which produce nail surface changes such as trachyonychia, pitting and ridging. Mostly, this is a neglected area due to the dearth of treatment options. Glycolic acid peeling has been reported to be effective in such cases. AIM: This study aims to assess the safety and efficacy of medium depth peels (70% glycolic acid versus phenol combination peel [8% phenol with 15% trichloroacetic acid]) in patients with superficial nail abnormalities. MATERIALS AND METHODS: A right-left comparative study in patients with superficial nail abnormalities was done. On the right finger or toenails phenol combination peels and on the left side 70% glycolic acid was used in a predefined protocol over 12 weeks. The severity was assessed objectively by a new devised index (Nail Surface abnormality Index (NSI]). Patient's subjective perception of severity was assessed by Visual Analogue Scale (VAS), and that of the physician was assessed by Physician's Global Assessment (PGA) scores. RESULTS: A total of 17 patients were enrolled, two dropped out and 15 patients were included in the final analysis (mean age 19.2 years, total 120 nails treated). The mean NSI score declined from 7.88 ± 0.45 to 4.02 ± 0.45 on the right side; and from 8.0 ± 0.45 to 4.32 ± 0.44 on left side, at the end of 12 weeks. The VAS declined from 6.57 ± 0.26 to 3.87 ± 0.33 on right side and from 6.32 ± 0.28 to 3.78 ± 0.32 on left side. According to PGA score, five patients showed good improvement, seven showed moderate improvement and three responded poorly. CONCLUSION: Both the medium depth peels were found to be safe and equally efficacious modalities for treatment of superficial nail abnormalities. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5418978/ /pubmed/28529418 http://dx.doi.org/10.4103/0974-2077.204580 Text en Copyright: © 2017 Journal of Cutaneous and Aesthetic Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Daulatabad, Deepashree
Nanda, Soni
Grover, Chander
Intra-individual Right-left Comparative Study of Medium Depth Peels in Superficial Nail Abnormalities
title Intra-individual Right-left Comparative Study of Medium Depth Peels in Superficial Nail Abnormalities
title_full Intra-individual Right-left Comparative Study of Medium Depth Peels in Superficial Nail Abnormalities
title_fullStr Intra-individual Right-left Comparative Study of Medium Depth Peels in Superficial Nail Abnormalities
title_full_unstemmed Intra-individual Right-left Comparative Study of Medium Depth Peels in Superficial Nail Abnormalities
title_short Intra-individual Right-left Comparative Study of Medium Depth Peels in Superficial Nail Abnormalities
title_sort intra-individual right-left comparative study of medium depth peels in superficial nail abnormalities
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418978/
https://www.ncbi.nlm.nih.gov/pubmed/28529418
http://dx.doi.org/10.4103/0974-2077.204580
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