A Cre Transcription Fidelity Reporter Identifies GreA as a Major RNA Proofreading Factor in Escherichia coli

We made a coupled genetic reporter that detects rare transcription misincorporation errors to measure RNA polymerase transcription fidelity in Escherichia coli. Using this reporter, we demonstrated in vivo that the transcript cleavage factor GreA, but not GreB, is essential for proofreading of a tra...

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Detalles Bibliográficos
Autores principales: Bubunenko, Mikhail G., Court, Carolyn B., Rattray, Alison J., Gotte, Deanna R., Kireeva, Maria L., Irizarry-Caro, Jorge A., Li, Xintian, Jin, Ding J., Court, Donald L., Strathern, Jeffrey N., Kashlev, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419468/
https://www.ncbi.nlm.nih.gov/pubmed/28341651
http://dx.doi.org/10.1534/genetics.116.198960

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