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Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca(2+)]i overload and NF-κB activation

Prolactin (PRL) is a peptidic hormone that displays pleiotropic functions in the organism including different actions in the brain. PRL exerts a neuroprotective effect against excitotoxicity produced by glutamate (Glu) or kainic acid in both in vitro and in vivo models. It is well known that Glu exc...

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Detalles Bibliográficos
Autores principales: Rivero-Segura, Nadia A., Flores-Soto, Edgar, García de la Cadena, Selene, Coronado-Mares, Isabel, Gomez-Verjan, Juan C., Ferreira, Diana G., Cabrera-Reyes, Erika Alejandra, Lopes, Luísa V., Massieu, Lourdes, Cerbón, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419567/
https://www.ncbi.nlm.nih.gov/pubmed/28475602
http://dx.doi.org/10.1371/journal.pone.0176910