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Blocking Smad2 signalling with loganin attenuates SW10 cell cycle arrest induced by TNF-α
The activity of Schwann cells (SWCs) is very important in trauma-induced nerve repair, and tumour necrosis factor-α (TNF-α) produced during tissue injury inhibits the viability of SWCs, which delays the repair of peripheral nerves. Loganin is an iridoid glycoside that has been shown to alleviate a v...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419568/ https://www.ncbi.nlm.nih.gov/pubmed/28475649 http://dx.doi.org/10.1371/journal.pone.0176965 |