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Expression of CD33 is a predictive factor for effect of Gemtuzumab Ozogamicin at different doses in adult acute myeloid leukemia
It remains unclear in adult acute myeloid leukemia (AML) whether leukemic expression of CD33, the target antigen for Gemtuzumab Ozogamicin (GO), add prognostic information on GO effectiveness at different doses. CD33 expression quantified in 1583 patients recruited to UK-NCRI-AML17 (younger adults)...
Autores principales: | Khan, Naeem, Hills, Robert K, Virgo, Paul, Couzens, Stephen, Clark, Nithiya, Gilkes, Amanda, Richardson, Peter, Knapper, Steven, Grimwade, David, Russell, Nigel H, Burnett, Alan K, Freeman, Sylvie D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419583/ https://www.ncbi.nlm.nih.gov/pubmed/27795558 http://dx.doi.org/10.1038/leu.2016.309 |
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