Plasmodium falciparum histidine-rich protein II causes vascular leakage and exacerbates experimental cerebral malaria in mice

A devastating complication of Plasmodium falciparum infection is cerebral malaria, in which vascular leakage and cerebral swelling lead to coma and often death. P. falciparum produces a protein called histidine-rich protein II (HRPII) that accumulates to high levels in the bloodstream of patients an...

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Detalles Bibliográficos
Autores principales: Pal, Priya, Balaban, Amanda E., Diamond, Michael S., Sinnis, Photini, Klein, Robyn S., Goldberg, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419595/
https://www.ncbi.nlm.nih.gov/pubmed/28475625
http://dx.doi.org/10.1371/journal.pone.0177142

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