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SUSD2 promotes tumor-associated macrophage recruitment by increasing levels of MCP-1 in breast cancer
Tumor-associated macrophages (TAMs) play a role in tumor angiogenesis and are recruited into the tumor microenvironment (TME) by secreted chemokines, including Monocyte Chemoattractant Protein-1 (MCP-1/CCL2). Angiogenesis is required to sustain proliferation and enable metastasis of breast cancer (B...
Autores principales: | Hultgren, Elizabeth M., Patrick, Mitch E., Evans, Rick L., Stoos, Catherine T., Egland, Kristi A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419604/ https://www.ncbi.nlm.nih.gov/pubmed/28475599 http://dx.doi.org/10.1371/journal.pone.0177089 |
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