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Signals of vagal circuits engaging with AKT1 in α7 nAChR(+)CD11b(+) cells lessen E. coli and LPS-induced acute inflammatory injury

Vagal circuits-α7 nAChR (α7 nicotinic acetylcholine receptor, coded by Chrna7) signaling utilizes spleen as a hub to dampen systemic inflammatory responses. Vagal innervations also extend to the distal airways and alveoli. Vagotomy and deficiency of α7 nAChR deteriorate E. coli and lipopolysaccharid...

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Detalles Bibliográficos
Autores principales:	Zhao, Caiqi, Yang, Xi, Su, Emily M, Huang, Yuanyuan, Li, Ling, Matthay, Michael A, Su, Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419718/ https://www.ncbi.nlm.nih.gov/pubmed/28529765 http://dx.doi.org/10.1038/celldisc.2017.9

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