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Single-molecule visualization of fast polymerase turnover in the bacterial replisome

The Escherichia coli DNA replication machinery has been used as a road map to uncover design rules that enable DNA duplication with high efficiency and fidelity. Although the enzymatic activities of the replicative DNA Pol III are well understood, its dynamics within the replisome are not. Here, we...

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Detalles Bibliográficos
Autores principales:	Lewis, Jacob S, Spenkelink, Lisanne M, Jergic, Slobodan, Wood, Elizabeth A, Monachino, Enrico, Horan, Nicholas P, Duderstadt, Karl E, Cox, Michael M, Robinson, Andrew, Dixon, Nicholas E, van Oijen, Antoine M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419744/ https://www.ncbi.nlm.nih.gov/pubmed/28432790 http://dx.doi.org/10.7554/eLife.23932

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