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Dectin-1 Activation on Macrophages by Galectin-9 Promotes Pancreatic Carcinoma and Peritumoral Immune-Tolerance
The progression of pancreatic oncogenesis requires immune-suppressive inflammation in cooperation with oncogenic mutations. However, the drivers of intra-tumoral immune tolerance are uncertain. Dectin-1 is an innate immune receptor critical in anti-fungal immunity, but its role in sterile inflammati...
Autores principales: | Daley, Donnele, Mani, Vishnu R., Mohan, Navyatha, Akkad, Neha, Ochi, Atsuo, Heindel, Daniel W., Lee, Ki Buom, Zambirinis, Constantinos P., Pandian, Gautam S.D. Balasubramania, Savadkar, Shivraj, Torres-Hernandez, Alejandro, Nayak, Shruti, Wang, Ding, Hundeyin, Mautin, Diskin, Brian, Aykut, Berk, Werba, Gregor, Barilla, Rocky M., Rodriguez, Robert, Chang, Steven, Gardner, Lawrence, Mahal, Lara K., Ueberheide, Beatrix, Miller, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419876/ https://www.ncbi.nlm.nih.gov/pubmed/28394331 http://dx.doi.org/10.1038/nm.4314 |
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