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Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease

OBJECTIVE: To identify regional brain metabolic dysfunctions associated with neuropsychiatric symptoms (NPS) in preclinical Alzheimer disease (AD). METHODS: We stratified 115 cognitively normal individuals into preclinical AD (both amyloid and tau pathologies present), asymptomatic at risk for AD (e...

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Detalles Bibliográficos
Autores principales: Ng, Kok Pin, Pascoal, Tharick A., Mathotaarachchi, Sulantha, Chung, Chang-Oh, Benedet, Andréa L., Shin, Monica, Kang, Min Su, Li, Xiaofeng, Ba, Maowen, Kandiah, Nagaendran, Rosa-Neto, Pedro, Gauthier, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419982/
https://www.ncbi.nlm.nih.gov/pubmed/28404803
http://dx.doi.org/10.1212/WNL.0000000000003916