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Adipose tissue lipolysis and remodeling during the transition period of dairy cows
Elevated concentrations of plasma fatty acids in transition dairy cows are significantly associated with increased disease susceptibility and poor lactation performance. The main source of plasma fatty acids throughout the transition period is lipolysis from adipose tissue depots. During this time,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420123/ https://www.ncbi.nlm.nih.gov/pubmed/28484594 http://dx.doi.org/10.1186/s40104-017-0174-4 |
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author | Contreras, G. Andres Strieder-Barboza, Clarissa Raphael, William |
author_facet | Contreras, G. Andres Strieder-Barboza, Clarissa Raphael, William |
author_sort | Contreras, G. Andres |
collection | PubMed |
description | Elevated concentrations of plasma fatty acids in transition dairy cows are significantly associated with increased disease susceptibility and poor lactation performance. The main source of plasma fatty acids throughout the transition period is lipolysis from adipose tissue depots. During this time, plasma fatty acids serve as a source of calories mitigating the negative energy balance prompted by copious milk synthesis and limited dry matter intake. Past research has demonstrated that lipolysis in the adipose organ is a complex process that includes not only the activation of lipolytic pathways in response to neural, hormonal, or paracrine stimuli, but also important changes in the structure and cellular distribution of the tissue in a process known as adipose tissue remodeling. This process involves an inflammatory response with immune cell migration, proliferation of the cellular components of the stromal vascular fraction, and changes in the extracellular matrix. This review summarizes current knowledge on lipolysis in dairy cattle, expands on the new field of adipose tissue remodeling, and discusses how these biological processes affect transition cow health and productivity. |
format | Online Article Text |
id | pubmed-5420123 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-54201232017-05-08 Adipose tissue lipolysis and remodeling during the transition period of dairy cows Contreras, G. Andres Strieder-Barboza, Clarissa Raphael, William J Anim Sci Biotechnol Review Elevated concentrations of plasma fatty acids in transition dairy cows are significantly associated with increased disease susceptibility and poor lactation performance. The main source of plasma fatty acids throughout the transition period is lipolysis from adipose tissue depots. During this time, plasma fatty acids serve as a source of calories mitigating the negative energy balance prompted by copious milk synthesis and limited dry matter intake. Past research has demonstrated that lipolysis in the adipose organ is a complex process that includes not only the activation of lipolytic pathways in response to neural, hormonal, or paracrine stimuli, but also important changes in the structure and cellular distribution of the tissue in a process known as adipose tissue remodeling. This process involves an inflammatory response with immune cell migration, proliferation of the cellular components of the stromal vascular fraction, and changes in the extracellular matrix. This review summarizes current knowledge on lipolysis in dairy cattle, expands on the new field of adipose tissue remodeling, and discusses how these biological processes affect transition cow health and productivity. BioMed Central 2017-05-05 /pmc/articles/PMC5420123/ /pubmed/28484594 http://dx.doi.org/10.1186/s40104-017-0174-4 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Contreras, G. Andres Strieder-Barboza, Clarissa Raphael, William Adipose tissue lipolysis and remodeling during the transition period of dairy cows |
title | Adipose tissue lipolysis and remodeling during the transition period of dairy cows |
title_full | Adipose tissue lipolysis and remodeling during the transition period of dairy cows |
title_fullStr | Adipose tissue lipolysis and remodeling during the transition period of dairy cows |
title_full_unstemmed | Adipose tissue lipolysis and remodeling during the transition period of dairy cows |
title_short | Adipose tissue lipolysis and remodeling during the transition period of dairy cows |
title_sort | adipose tissue lipolysis and remodeling during the transition period of dairy cows |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420123/ https://www.ncbi.nlm.nih.gov/pubmed/28484594 http://dx.doi.org/10.1186/s40104-017-0174-4 |
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