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Efficacy and safety of rebamipide liquid for chemoradiotherapy-induced oral mucositis in patients with head and neck cancer: a multicenter, randomized, double-blind, placebo-controlled, parallel-group phase II study
BACKGROUND: Recent preclinical and phase I studies have reported that rebamipide decreased the severity of chemoradiotherapy-induced oral mucositis in patients with oral cancer. This placebo-controlled randomized phase II study assessed the clinical benefit of rebamipide in reducing the incidence of...
Autores principales: | Yokota, T., Ogawa, T., Takahashi, S., Okami, K., Fujii, T., Tanaka, K., Iwae, S., Ota, I., Ueda, T., Monden, N., Matsuura, K., Kojima, H., Ueda, S., Sasaki, K., Fujimoto, Y., Hasegawa, Y., Beppu, T., Nishimori, H., Hirano, S., Naka, Y., Matsushima, Y., Fujii, M., Tahara, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420134/ https://www.ncbi.nlm.nih.gov/pubmed/28476132 http://dx.doi.org/10.1186/s12885-017-3295-4 |
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