Cytomegalovirus, Macrophages and Breast Cancer

The human cytomegalovirus (HCMV) is a betaherpesvirus that is highly host specific, infects among others epithelial cells and macrophages, and has been recently mentioned as having oncomodulatory properties. HCMV is detected in the breast tumor tissue where macrophages, especially tumor associated m...

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Detalles Bibliográficos
Autores principales: Pasquereau, S., Al Moussawi, F., Karam, W., Diab Assaf, M., Kumar, A., Herbein, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420183/
https://www.ncbi.nlm.nih.gov/pubmed/28567162
http://dx.doi.org/10.2174/1874357901711010015
Descripción
Sumario:The human cytomegalovirus (HCMV) is a betaherpesvirus that is highly host specific, infects among others epithelial cells and macrophages, and has been recently mentioned as having oncomodulatory properties. HCMV is detected in the breast tumor tissue where macrophages, especially tumor associated macrophages, are associated with a poor prognosis. In this review, we will discuss the potential implication of HCMV in breast cancer with emphasis on the role played by macrophages.

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