Cytomegalovirus, Macrophages and Breast Cancer

The human cytomegalovirus (HCMV) is a betaherpesvirus that is highly host specific, infects among others epithelial cells and macrophages, and has been recently mentioned as having oncomodulatory properties. HCMV is detected in the breast tumor tissue where macrophages, especially tumor associated m...

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Detalles Bibliográficos
Autores principales: Pasquereau, S., Al Moussawi, F., Karam, W., Diab Assaf, M., Kumar, A., Herbein, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420183/
https://www.ncbi.nlm.nih.gov/pubmed/28567162
http://dx.doi.org/10.2174/1874357901711010015
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author Pasquereau, S.
Al Moussawi, F.
Karam, W.
Diab Assaf, M.
Kumar, A.
Herbein, G.
author_facet Pasquereau, S.
Al Moussawi, F.
Karam, W.
Diab Assaf, M.
Kumar, A.
Herbein, G.
author_sort Pasquereau, S.
collection PubMed
description The human cytomegalovirus (HCMV) is a betaherpesvirus that is highly host specific, infects among others epithelial cells and macrophages, and has been recently mentioned as having oncomodulatory properties. HCMV is detected in the breast tumor tissue where macrophages, especially tumor associated macrophages, are associated with a poor prognosis. In this review, we will discuss the potential implication of HCMV in breast cancer with emphasis on the role played by macrophages.
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spelling pubmed-54201832017-05-31 Cytomegalovirus, Macrophages and Breast Cancer Pasquereau, S. Al Moussawi, F. Karam, W. Diab Assaf, M. Kumar, A. Herbein, G. Open Virol J Article The human cytomegalovirus (HCMV) is a betaherpesvirus that is highly host specific, infects among others epithelial cells and macrophages, and has been recently mentioned as having oncomodulatory properties. HCMV is detected in the breast tumor tissue where macrophages, especially tumor associated macrophages, are associated with a poor prognosis. In this review, we will discuss the potential implication of HCMV in breast cancer with emphasis on the role played by macrophages. Bentham Open 2017-03-31 /pmc/articles/PMC5420183/ /pubmed/28567162 http://dx.doi.org/10.2174/1874357901711010015 Text en © 2017 Pasquereau et al. https://creativecommons.org/licenses/by/4.0/legalcode This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Pasquereau, S.
Al Moussawi, F.
Karam, W.
Diab Assaf, M.
Kumar, A.
Herbein, G.
Cytomegalovirus, Macrophages and Breast Cancer
title Cytomegalovirus, Macrophages and Breast Cancer
title_full Cytomegalovirus, Macrophages and Breast Cancer
title_fullStr Cytomegalovirus, Macrophages and Breast Cancer
title_full_unstemmed Cytomegalovirus, Macrophages and Breast Cancer
title_short Cytomegalovirus, Macrophages and Breast Cancer
title_sort cytomegalovirus, macrophages and breast cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420183/
https://www.ncbi.nlm.nih.gov/pubmed/28567162
http://dx.doi.org/10.2174/1874357901711010015
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