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Perseveration in a spatial-discrimination serial reversal learning task is differentially affected by MAO-A and MAO-B inhibition and associated with reduced anxiety and peripheral serotonin levels

RATIONALE: Impairments in behavioral flexibility lie at the core of anxiety and obsessive-compulsive disorders. Few studies, however, have investigated the neural substrates of natural variation in behavioral flexibility and whether inflexible behavior is linked to anxiety and peripheral markers of...

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Detalles Bibliográficos
Autores principales: Zhukovsky, Peter, Alsiö, Johan, Jupp, Bianca, Xia, Jing, Guiliano, Chiara, Jenner, Lucy, Griffiths, Jessica, Riley, Errin, Ali, Sajeed, Roberts, Angela C., Robbins, Trevor W., Dalley, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420387/
https://www.ncbi.nlm.nih.gov/pubmed/28251298
http://dx.doi.org/10.1007/s00213-017-4569-x