Adenocarcinoma In Situ Arising from Brunner's Gland Treated by Endoscopic Mucosal Resection

An 86-year-old Japanese man was presented to our hospital for further investigation of duodenal adenocarcinoma. The tumor was endoscopically resected. Pathological analysis revealed coexistence of gastric foveolar metaplasia and a surrounding hyperplastic Brunner's gland, in addition to an aden...

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Autores principales: Iwamuro, Masaya, Kobayashi, Sayo, Ohara, Nobuya, Kawano, Seiji, Kawahara, Yoshiro, Okada, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420418/
https://www.ncbi.nlm.nih.gov/pubmed/28512587
http://dx.doi.org/10.1155/2017/7916976
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author Iwamuro, Masaya
Kobayashi, Sayo
Ohara, Nobuya
Kawano, Seiji
Kawahara, Yoshiro
Okada, Hiroyuki
author_facet Iwamuro, Masaya
Kobayashi, Sayo
Ohara, Nobuya
Kawano, Seiji
Kawahara, Yoshiro
Okada, Hiroyuki
author_sort Iwamuro, Masaya
collection PubMed
description An 86-year-old Japanese man was presented to our hospital for further investigation of duodenal adenocarcinoma. The tumor was endoscopically resected. Pathological analysis revealed coexistence of gastric foveolar metaplasia and a surrounding hyperplastic Brunner's gland, in addition to an adenocarcinoma component. Immunostaining for MUC5AC and MUC6 confirmed the diagnosis of adenocarcinoma in situ arising from Brunner's gland hyperplasia. This case suggests that although detailed preoperative evaluation is required to determine the depth of tumor invasion, endoscopic resection may be a promising option for the treatment of adenocarcinomas arising from Brunner's gland hyperplasia.
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spelling pubmed-54204182017-05-16 Adenocarcinoma In Situ Arising from Brunner's Gland Treated by Endoscopic Mucosal Resection Iwamuro, Masaya Kobayashi, Sayo Ohara, Nobuya Kawano, Seiji Kawahara, Yoshiro Okada, Hiroyuki Case Rep Gastrointest Med Case Report An 86-year-old Japanese man was presented to our hospital for further investigation of duodenal adenocarcinoma. The tumor was endoscopically resected. Pathological analysis revealed coexistence of gastric foveolar metaplasia and a surrounding hyperplastic Brunner's gland, in addition to an adenocarcinoma component. Immunostaining for MUC5AC and MUC6 confirmed the diagnosis of adenocarcinoma in situ arising from Brunner's gland hyperplasia. This case suggests that although detailed preoperative evaluation is required to determine the depth of tumor invasion, endoscopic resection may be a promising option for the treatment of adenocarcinomas arising from Brunner's gland hyperplasia. Hindawi 2017 2017-04-23 /pmc/articles/PMC5420418/ /pubmed/28512587 http://dx.doi.org/10.1155/2017/7916976 Text en Copyright © 2017 Masaya Iwamuro et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Iwamuro, Masaya
Kobayashi, Sayo
Ohara, Nobuya
Kawano, Seiji
Kawahara, Yoshiro
Okada, Hiroyuki
Adenocarcinoma In Situ Arising from Brunner's Gland Treated by Endoscopic Mucosal Resection
title Adenocarcinoma In Situ Arising from Brunner's Gland Treated by Endoscopic Mucosal Resection
title_full Adenocarcinoma In Situ Arising from Brunner's Gland Treated by Endoscopic Mucosal Resection
title_fullStr Adenocarcinoma In Situ Arising from Brunner's Gland Treated by Endoscopic Mucosal Resection
title_full_unstemmed Adenocarcinoma In Situ Arising from Brunner's Gland Treated by Endoscopic Mucosal Resection
title_short Adenocarcinoma In Situ Arising from Brunner's Gland Treated by Endoscopic Mucosal Resection
title_sort adenocarcinoma in situ arising from brunner's gland treated by endoscopic mucosal resection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420418/
https://www.ncbi.nlm.nih.gov/pubmed/28512587
http://dx.doi.org/10.1155/2017/7916976
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