Association of PECAM-1 Gene Polymorphisms with Kawasaki Disease in Chinese Children

Kawasaki disease (KD) is an acute systemic vasculitis complicated by development of coronary artery lesions. PECAM-1 is a kind of cell adhesion molecule, which plays an important role in coronary artery disease. The relationship between PECAM-1 gene polymorphisms and their susceptibility to Kawasaki...

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Detalles Bibliográficos
Autores principales: Li, Zhuoying, Han, Dong, Jiang, Jie, Chen, Jia, Tian, Lang, Yang, Zuocheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420431/
https://www.ncbi.nlm.nih.gov/pubmed/28512385
http://dx.doi.org/10.1155/2017/2960502
Descripción
Sumario:Kawasaki disease (KD) is an acute systemic vasculitis complicated by development of coronary artery lesions. PECAM-1 is a kind of cell adhesion molecule, which plays an important role in coronary artery disease. The relationship between PECAM-1 gene polymorphisms and their susceptibility to Kawasaki diseases (KD) is still unclear. In our study, we examined the PECAM-1 gene polymorphisms in 44 KD patients and 59 healthy children and revealed the correlation of PECAM-1 gene polymorphisms in KD children with and without coronary artery lesions (CAL).

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