Oncostatin M drives intestinal inflammation in mice and its abundance predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease

Inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are complex chronic inflammatory conditions of the gastrointestinal tract that are driven by perturbed cytokine pathways. Anti-tumor necrosis factor-α (TNF) antibodies are a mainstay therapeutic approach f...

Descripción completa

Detalles Bibliográficos
Autores principales: West, Nathaniel R., Hegazy, Ahmed N., Owens, Benjamin M. J., Bullers, Samuel J., Linggi, Bryan, Buonocore, Sofia, Coccia, Margherita, Görtz, Dieter, This, Sébastien, Stockenhuber, Krista, Pott, Johanna, Friedrich, Matthias, Ryzhakov, Grigory, Baribaud, Frédéric, Brodmerkel, Carrie, Cieluch, Constanze, Rahman, Nahid, Müller-Newen, Gerhard, Owens, Raymond J., Kühl, Anja A., Maloy, Kevin J., Plevy, Scott E., Keshav, Satish, Travis, Simon P. L., Powrie, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420447/
https://www.ncbi.nlm.nih.gov/pubmed/28368383
http://dx.doi.org/10.1038/nm.4307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420447/
https://www.ncbi.nlm.nih.gov/pubmed/28368383
http://dx.doi.org/10.1038/nm.4307

Ejemplares similares