Thymosin α1 represents a potential potent single molecule-based therapy for cystic fibrosis

Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) that compromise its chloride-channel activity. The most common mutation, p.Phe508del, results in the production of a misfolded CFTR protein, which has residual channel acti...

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Detalles Bibliográficos
Autores principales: Romani, Luigina, Oikonomou, Vasilis, Moretti, Silvia, Iannitti, Rossana G., D’Adamo, Maria Cristina, Villella, Valeria R., Pariano, Marilena, Sforna, Luigi, Borghi, Monica, Bellet, Marina M., Fallarino, Francesca, Pallotta, Maria Teresa, Servillo, Giuseppe, Ferrari, Eleonora, Puccetti, Paolo, Kroemer, Guido, Pessia, Mauro, Maiuri, Luigi, Goldstein, Allan L., Garaci, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420451/
https://www.ncbi.nlm.nih.gov/pubmed/28394330
http://dx.doi.org/10.1038/nm.4305

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