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PIN1 Modulates Huntingtin Levels and Aggregate Accumulation: An In vitro Model

Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder characterized by a polyglutamine expansion within the N-terminal region of huntingtin protein (HTT). Cellular mechanisms promoting mutant huntingtin (mHTT) clearance are of great interest in HD pathology as they can...

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Detalles Bibliográficos
Autores principales:	Carnemolla, Alisia, Michelazzi, Silvia, Agostoni, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420564/ https://www.ncbi.nlm.nih.gov/pubmed/28533744 http://dx.doi.org/10.3389/fncel.2017.00121

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