Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells

Giant amphiphiles encompassing a hydrophilic β-cyclodextrin (βCD) component and a hydrophobic calix[4]arene (CA(4)) module undergo self-assembly in aqueous media to afford core-shell nanospheres or nanocapsules, depending on the nanoprecipitation protocol, with high docetaxel (DTX) loading capacity....

Descripción completa

Detalles Bibliográficos
Autores principales: Gallego-Yerga, Laura, Posadas, Inmaculada, de la Torre, Cristina, Ruiz-Almansa, Jesús, Sansone, Francesco, Ortiz Mellet, Carmen, Casnati, Alessandro, García Fernández, José M., Ceña, Valentín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420566/
https://www.ncbi.nlm.nih.gov/pubmed/28533751
http://dx.doi.org/10.3389/fphar.2017.00249

Ejemplares similares

Ejemplares similares