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Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML
We sought to identify drugs that could counteract cytarabine resistance in acute myeloid leukemia (AML) by generating eight resistant variants from MOLM-13 and SHI-1 AML cell lines by long-term drug treatment. These cells were compared with 66 ex vivo chemorefractory samples from cytarabine-treated...
Autores principales: | Malani, D, Murumägi, A, Yadav, B, Kontro, M, Eldfors, S, Kumar, A, Karjalainen, R, Majumder, M M, Ojamies, P, Pemovska, T, Wennerberg, K, Heckman, C, Porkka, K, Wolf, M, Aittokallio, T, Kallioniemi, O |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420795/ https://www.ncbi.nlm.nih.gov/pubmed/27833094 http://dx.doi.org/10.1038/leu.2016.314 |
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