High prevalence of TP53 mutations is associated with poor survival and an EMT signature in gliosarcoma patients

Gliosarcoma (GS) is a rare variant (2%) of glioblastoma (GBM) that poses clinical genomic challenges because of its poor prognosis and limited genomic information. To gain a comprehensive view of the genomic alterations in GS and to understand the molecular etiology of GS, we applied whole-exome seq...

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Detalles Bibliográficos
Autores principales: Cho, Sung-Yup, Park, Changho, Na, Deukchae, Han, Jee Yun, Lee, Jieun, Park, Ok-Kyoung, Zhang, Chengsheng, Sung, Chang Ohk, Moon, Hyo Eun, Kim, Yona, Kim, Jeong Hoon, Kim, Jong Jae, Khang, Shin Kwang, Nam, Do-Hyun, Choi, Jung Won, Suh, Yeon-Lim, Kim, Dong Gyu, Park, Sung Hye, Youn, Hyewon, Yun, Kyuson, Kim, Jong-Il, Lee, Charles, Paek, Sun Ha, Park, Hansoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420801/
https://www.ncbi.nlm.nih.gov/pubmed/28408749
http://dx.doi.org/10.1038/emm.2017.9

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