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Screening of conventional anticonvulsants in a genetic mouse model of epilepsy

OBJECTIVE: Epilepsy is a common neurological disorder that affects 1% of the population. Approximately, 30% of individuals with epilepsy are refractory to treatment, highlighting the need for novel therapies. Conventional anticonvulsant screening relies predominantly on induced seizure models. Howev...

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Detalles Bibliográficos
Autores principales: Hawkins, Nicole A., Anderson, Lyndsey L., Gertler, Tracy S., Laux, Linda, George, Alfred L., Kearney, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420810/
https://www.ncbi.nlm.nih.gov/pubmed/28491900
http://dx.doi.org/10.1002/acn3.413