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Beta Cell Formation in vivo Through Cellular Networking, Integration and Processing (CNIP) in Wild Type Adult Mice

Insulin replacement therapy is essential in type 1 diabetic individuals and is required in ~40-50% of type 2 diabetics during their lifetime. Prior attempts at beta cell regeneration have relied upon pancreatic injury to induce beta cell proliferation, dedifferentiation and activation of the embryon...

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Detalles Bibliográficos
Autores principales: Doiron, Bruno, Hu, Wenchao, DeFronzo, Ralph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421132/
https://www.ncbi.nlm.nih.gov/pubmed/26696016
http://dx.doi.org/10.2174/1389201017666151223124031