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Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions

Lymphocyte transendothelial migration (TEM) is critically dependent on intraendothelial signaling triggered by adhesion to ICAM-1. Here we show that endothelial MAPKs ERK, p38, and JNK mediate diapedesis-related and diapedesis-unrelated functions of ICAM-1 in cerebral and dermal microvascular endoth...

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Detalles Bibliográficos
Autores principales:	Dragoni, Silvia, Hudson, Natalie, Kenny, Bridget-Ann, Burgoyne, Thomas, McKenzie, Jenny A., Gill, Yadvinder, Blaber, Robert, Futter, Clare E., Adamson, Peter, Greenwood, John, Turowski, Patric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2017
Materias:	Innate Immunity and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421301/ https://www.ncbi.nlm.nih.gov/pubmed/28373581 http://dx.doi.org/10.4049/jimmunol.1600823

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