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Critical attributes of human early mesenchymal stromal cell-laden microcarrier constructs for improved chondrogenic differentiation

BACKGROUND: Microcarrier cultures which are useful for producing large cell numbers can act as scaffolds to create stem cell-laden microcarrier constructs for cartilage tissue engineering. However, the critical attributes required to achieve efficient chondrogenic differentiation for such constructs...

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Detalles Bibliográficos
Autores principales: Lin, Youshan Melissa, Lee, Jialing, Lim, Jessica Fang Yan, Choolani, Mahesh, Chan, Jerry Kok Yen, Reuveny, Shaul, Oh, Steve Kah Weng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421335/
https://www.ncbi.nlm.nih.gov/pubmed/28482913
http://dx.doi.org/10.1186/s13287-017-0538-x