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Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis

INTRODUCTION: Seborrheic dermatitis is a chronic inflammatory skin disease. One of the components of metabolic syndrome is inflammation, and many inflammatory cytokines play a critical role in the disease. The aim of this study is to investigate metabolic syndrome and to evaluate the relationship be...

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Autores principales: Imamoglu, Betul, Hayta, Sibel Berksoy, Guner, Rukiye, Akyol, Melih, Ozcelik, Sedat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421546/
https://www.ncbi.nlm.nih.gov/pubmed/28905039
http://dx.doi.org/10.5114/amsad.2016.65075
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author Imamoglu, Betul
Hayta, Sibel Berksoy
Guner, Rukiye
Akyol, Melih
Ozcelik, Sedat
author_facet Imamoglu, Betul
Hayta, Sibel Berksoy
Guner, Rukiye
Akyol, Melih
Ozcelik, Sedat
author_sort Imamoglu, Betul
collection PubMed
description INTRODUCTION: Seborrheic dermatitis is a chronic inflammatory skin disease. One of the components of metabolic syndrome is inflammation, and many inflammatory cytokines play a critical role in the disease. The aim of this study is to investigate metabolic syndrome and to evaluate the relationship between the parameters of the disease and disease severity in patients with seborrheic dermatitis. MATERIAL AND METHODS: Forty-seven patients with seborrheic dermatitis and 36 healthy controls were included in the study. The parameters of metabolic syndrome were recorded in both groups. In the patient group, disease severity was determined with the seborrheic dermatitis area and severity index (SDASI). All the venous blood samples were taken at 8 a.m. after 10 h of fasting. RESULTS: High-density lipoprotein (HDL) levels in the patient group were statistically significantly lower than in the controls. There was no significant difference between groups according to other parameters. In terms of history of metabolic disease in first degree relatives (diabetes mellitus, cardiovascular disease, and dyslipidaemia), 78.7% of those in the patient group (n = 37) and 55.6% of those in the control group (n = 20) had a history of metabolic disease in their families, and the difference between the patient and control groups was found to be statistically significant (p < 0.05). There was a significant correlation between disease severity and plasma HDL levels (p = 0.033, r = –0.312). CONCLUSIONS: The presence of seborrheic dermatitis may be a predictive factor for metabolic syndrome.
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spelling pubmed-54215462017-09-13 Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis Imamoglu, Betul Hayta, Sibel Berksoy Guner, Rukiye Akyol, Melih Ozcelik, Sedat Arch Med Sci Atheroscler Dis Clinical Research INTRODUCTION: Seborrheic dermatitis is a chronic inflammatory skin disease. One of the components of metabolic syndrome is inflammation, and many inflammatory cytokines play a critical role in the disease. The aim of this study is to investigate metabolic syndrome and to evaluate the relationship between the parameters of the disease and disease severity in patients with seborrheic dermatitis. MATERIAL AND METHODS: Forty-seven patients with seborrheic dermatitis and 36 healthy controls were included in the study. The parameters of metabolic syndrome were recorded in both groups. In the patient group, disease severity was determined with the seborrheic dermatitis area and severity index (SDASI). All the venous blood samples were taken at 8 a.m. after 10 h of fasting. RESULTS: High-density lipoprotein (HDL) levels in the patient group were statistically significantly lower than in the controls. There was no significant difference between groups according to other parameters. In terms of history of metabolic disease in first degree relatives (diabetes mellitus, cardiovascular disease, and dyslipidaemia), 78.7% of those in the patient group (n = 37) and 55.6% of those in the control group (n = 20) had a history of metabolic disease in their families, and the difference between the patient and control groups was found to be statistically significant (p < 0.05). There was a significant correlation between disease severity and plasma HDL levels (p = 0.033, r = –0.312). CONCLUSIONS: The presence of seborrheic dermatitis may be a predictive factor for metabolic syndrome. Termedia Publishing House 2016-12-30 /pmc/articles/PMC5421546/ /pubmed/28905039 http://dx.doi.org/10.5114/amsad.2016.65075 Text en Copyright: © 2016 Termedia & Banach http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Clinical Research
Imamoglu, Betul
Hayta, Sibel Berksoy
Guner, Rukiye
Akyol, Melih
Ozcelik, Sedat
Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis
title Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis
title_full Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis
title_fullStr Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis
title_full_unstemmed Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis
title_short Metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis
title_sort metabolic syndrome may be an important comorbidity in patients with seborrheic dermatitis
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421546/
https://www.ncbi.nlm.nih.gov/pubmed/28905039
http://dx.doi.org/10.5114/amsad.2016.65075
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