Cargando…
“Pro-dopamine regulation (KB220Z™)” as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in America
Since it is known that relapse, morality, and hospitalizations have been tied to the presence of the Dopamine D2 Receptor A1 allele, as one example, and carriers of this gene variant have a proclivity to favor amino-acid therapy, it seems intuitive that the incorporation of modalities to provide a b...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421552/ https://www.ncbi.nlm.nih.gov/pubmed/28491463 http://dx.doi.org/10.15761/JSIN.1000129 |
_version_ | 1783234607524610048 |
---|---|
author | Blum, K Marcelo, F Dushaj, K Fried, L Badgaiyan, RD |
author_facet | Blum, K Marcelo, F Dushaj, K Fried, L Badgaiyan, RD |
author_sort | Blum, K |
collection | PubMed |
description | Since it is known that relapse, morality, and hospitalizations have been tied to the presence of the Dopamine D2 Receptor A1 allele, as one example, and carriers of this gene variant have a proclivity to favor amino-acid therapy, it seems intuitive that the incorporation of modalities to provide a balance and or restoration of hypodopaminergia should be considered as a front-line tactic to overcome the current American opiate/opioid epidemic, saving millions from death and unwanted locked-in-addiction. If we continue down the prim road path of fighting addiction to narcotics with narcotics, we are doomed to fail. This lesson can also have global interest. |
format | Online Article Text |
id | pubmed-5421552 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
record_format | MEDLINE/PubMed |
spelling | pubmed-54215522017-05-08 “Pro-dopamine regulation (KB220Z™)” as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in America Blum, K Marcelo, F Dushaj, K Fried, L Badgaiyan, RD J Syst Integr Neurosci Article Since it is known that relapse, morality, and hospitalizations have been tied to the presence of the Dopamine D2 Receptor A1 allele, as one example, and carriers of this gene variant have a proclivity to favor amino-acid therapy, it seems intuitive that the incorporation of modalities to provide a balance and or restoration of hypodopaminergia should be considered as a front-line tactic to overcome the current American opiate/opioid epidemic, saving millions from death and unwanted locked-in-addiction. If we continue down the prim road path of fighting addiction to narcotics with narcotics, we are doomed to fail. This lesson can also have global interest. 2016-09 /pmc/articles/PMC5421552/ /pubmed/28491463 http://dx.doi.org/10.15761/JSIN.1000129 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Article Blum, K Marcelo, F Dushaj, K Fried, L Badgaiyan, RD “Pro-dopamine regulation (KB220Z™)” as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in America |
title | “Pro-dopamine regulation (KB220Z™)” as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in America |
title_full | “Pro-dopamine regulation (KB220Z™)” as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in America |
title_fullStr | “Pro-dopamine regulation (KB220Z™)” as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in America |
title_full_unstemmed | “Pro-dopamine regulation (KB220Z™)” as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in America |
title_short | “Pro-dopamine regulation (KB220Z™)” as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in America |
title_sort | “pro-dopamine regulation (kb220z™)” as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in america |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421552/ https://www.ncbi.nlm.nih.gov/pubmed/28491463 http://dx.doi.org/10.15761/JSIN.1000129 |
work_keys_str_mv | AT blumk prodopamineregulationkb220zasalongtermtherapeuticmodalitytoovercomereducedrestingstatedopaminetoneinopiateopioidepidemicinamerica AT marcelof prodopamineregulationkb220zasalongtermtherapeuticmodalitytoovercomereducedrestingstatedopaminetoneinopiateopioidepidemicinamerica AT dushajk prodopamineregulationkb220zasalongtermtherapeuticmodalitytoovercomereducedrestingstatedopaminetoneinopiateopioidepidemicinamerica AT friedl prodopamineregulationkb220zasalongtermtherapeuticmodalitytoovercomereducedrestingstatedopaminetoneinopiateopioidepidemicinamerica AT badgaiyanrd prodopamineregulationkb220zasalongtermtherapeuticmodalitytoovercomereducedrestingstatedopaminetoneinopiateopioidepidemicinamerica |