Withaferin A Inhibits Prostate Carcinogenesis in a PTEN-deficient Mouse Model of Prostate Cancer()()

We recently demonstrated that AKT activation plays a role in prostate cancer progression and inhibits the pro-apoptotic function of FOXO3a and Par-4. AKT inhibition and Par-4 induction suppressed prostate cancer progression in preclinical models. Here, we investigate the chemopreventive effect of th...

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Detalles Bibliográficos
Autores principales: Moselhy, Jim, Suman, Suman, Alghamdi, Mohammed, Chandarasekharan, Balaji, Das, Trinath P., Houda, Alatassi, Ankem, Murali, Damodaran, Chendil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421823/
https://www.ncbi.nlm.nih.gov/pubmed/28494348
http://dx.doi.org/10.1016/j.neo.2017.04.005

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