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Antitumor activity of sulfated hyaluronic acid fragments in pre-clinical models of bladder cancer

Tumor cell-derived hyaluronidase HYAL-1 degrades hyaluronic acid (HA) into angiogenic fragments (AGF: 10-12 disaccharides). AGF support tumor growth and progression. Urine and tissue HAase/HYAL-1 levels are sensitive markers for high-grade bladder cancer (BCa) and its metastasis. In preclinical mode...

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Detalles Bibliográficos
Autores principales:	Jordan, Andre R., Lokeshwar, Soum D., Lopez, Luis E., Hennig, Martin, Chipollini, Juan, Yates, Travis, Hupe, Marie C., Merseburger, Axel S., Shiedlin, Aviva, Cerwinka, Wolfgang H., Liu, Kebin, Lokeshwar, Vinata B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421845/ https://www.ncbi.nlm.nih.gov/pubmed/27419371 http://dx.doi.org/10.18632/oncotarget.10529

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