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The long noncoding RNA HOTAIR promotes Parkinson’s disease by upregulating LRRK2 expression

Long noncoding RNAs (lncRNAs) have emerged recently as a new class of genes that regulate cellular processes. HOTAIR (Hox transcript antisense intergenic RNA), an approximately 2.2 kb long noncoding RNA transcribed from the HOXC locus, is upregulated in various diseases. However, the role of HOTAIR...

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Detalles Bibliográficos
Autores principales: Wang, Sheng, Zhang, Xuan, Guo, Yuanyuan, Rong, Han, Liu, Tiebang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421861/
https://www.ncbi.nlm.nih.gov/pubmed/28445933
http://dx.doi.org/10.18632/oncotarget.15511

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