Combined MEK and Pi3′-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo

Anaplastic thyroid cancers and radioiodine resistant thyroid cancer are posing a major treat since surgery combined with Iodine(131) therapy is ineffective on them. Small-molecule inhibitors are presenting a new hope for patients, but often lead to drug resistance in many cancers. Based on the major...

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Detalles Bibliográficos
Autores principales: ElMokh, Oussama, Ruffieux-Daidié, Dorothée, Roelli, Matthias A, Stooss, Amandine, Phillips, Wayne A, Gertsch, Jürg, Dettmer, Matthias S, Charles, Roch-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421873/
https://www.ncbi.nlm.nih.gov/pubmed/28445948
http://dx.doi.org/10.18632/oncotarget.15599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421873/
https://www.ncbi.nlm.nih.gov/pubmed/28445948
http://dx.doi.org/10.18632/oncotarget.15599

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