Cargando…
Acid ceramidase is a novel drug target for pediatric brain tumors
Pediatric brain tumors are the most common solid tumors in children and are also a leading culprit of cancer-related fatalities in children. Pediatric brain tumors remain hard to treat. In this study, we demonstrated that medulloblastoma, pediatric glioblastoma, and atypical teratoid rhabdoid tumors...
Autores principales: | Doan, Ninh B., Nguyen, Ha S, Montoure, Andrew, Al-Gizawiy, Mona M., Mueller, Wade M., Kurpad, Shekar, Rand, Scott D., Connelly, Jennifer M., Chitambar, Christopher R., Schmainda, Kathleen M., Mirza, Shama P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421885/ https://www.ncbi.nlm.nih.gov/pubmed/28445970 http://dx.doi.org/10.18632/oncotarget.15800 |
Ejemplares similares
-
Acid ceramidase confers radioresistance to glioblastoma cells
por: Doan, Ninh B., et al.
Publicado: (2017) -
Acid ceramidase and its inhibitors: a de novo drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency
por: Doan, Ninh B., et al.
Publicado: (2017) -
Identification of radiation responsive genes and transcriptome profiling via complete RNA sequencing in a stable radioresistant U87 glioblastoma model
por: Doan, Ninh B., et al.
Publicado: (2018) -
Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy via genome-wide transcriptome changes
por: Alhajala, Hisham S., et al.
Publicado: (2018) -
HGG-06. CHARACTERIZATION OF THE EFFECT OF THE ORAL IRON-MIMETIC GALLIUM MALTOLATE ON PEDIATRIC GLIOBLASTOMA GROWTH IN VIVO
por: Al-Gizawiy, Mona M, et al.
Publicado: (2023)