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The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma

Toll-like receptor (TLR) ligands are strongly considered immune-adjuvants for cancer immunotherapy and have been shown to exert direct anti-cancer effects. This study was performed to evaluate the synergistic anti-cancer and anti-metastatic effects of the TLR7 agonist imiquimod (IMQ) during radiothe...

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Detalles Bibliográficos
Autores principales: Cho, Jeong Hyun, Lee, Hyo-Ji, Ko, Hyun-Jeong, Yoon, Byung-Il, Choe, Jongseon, Kim, Keun-Cheol, Hahn, Tae-Wook, Han, Jeong A., Choi, Sun Shim, Jung, Young Mee, Lee, Kee-Ho, Lee, Yun-Sil, Jung, Yu-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421900/
https://www.ncbi.nlm.nih.gov/pubmed/28212561
http://dx.doi.org/10.18632/oncotarget.15326