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The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma
Toll-like receptor (TLR) ligands are strongly considered immune-adjuvants for cancer immunotherapy and have been shown to exert direct anti-cancer effects. This study was performed to evaluate the synergistic anti-cancer and anti-metastatic effects of the TLR7 agonist imiquimod (IMQ) during radiothe...
Autores principales: | Cho, Jeong Hyun, Lee, Hyo-Ji, Ko, Hyun-Jeong, Yoon, Byung-Il, Choe, Jongseon, Kim, Keun-Cheol, Hahn, Tae-Wook, Han, Jeong A., Choi, Sun Shim, Jung, Young Mee, Lee, Kee-Ho, Lee, Yun-Sil, Jung, Yu-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421900/ https://www.ncbi.nlm.nih.gov/pubmed/28212561 http://dx.doi.org/10.18632/oncotarget.15326 |
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