MiR-124 acts as a tumor suppressor by inhibiting the expression of sphingosine kinase 1 and its downstream signaling in head and neck squamous cell carcinoma

By analyzing the expression profile of microRNAs in head and neck squamous cell carcinomas (HNSCC), we found that the expression level of miR-124 was 4.59-fold lower in tumors than in normal tissues. To understand its functions, we generated a miR-124-expressing subline (JHU-22(miR124)) and a mock v...

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Detalles Bibliográficos
Autores principales: Zhao, Yuan, Ling, Zhiqiang, Hao, Yubin, Pang, Xiaowu, Han, Xianlin, Califano, Joseph A., Shan, Liang, Gu, Xinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421905/
https://www.ncbi.nlm.nih.gov/pubmed/28212569
http://dx.doi.org/10.18632/oncotarget.15334

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