Cargando…
The aryl hydrocarbon receptor is required for induction of p21(cip1/waf1) expression and growth inhibition by SU5416 in hepatoma cells
The aryl hydrocarbon receptor (AhR) is a potential clinical target for cancer and autoimmune dysfunction. Identifying selective AhR modulators that produce desirable clinical outcomes represents an opportunity for developing new anti-cancer agents. Repurposing clinically-used drugs with established...
Autores principales: | O’Donnell, Edmond F., Jang, Hyo Sang, Pearce, Martin, Kerkvliet, Nancy I, Kolluri, Siva Kumar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421923/ https://www.ncbi.nlm.nih.gov/pubmed/28424418 http://dx.doi.org/10.18632/oncotarget.16056 |
Ejemplares similares
-
The Aryl Hydrocarbon Receptor Mediates Leflunomide-Induced Growth Inhibition of Melanoma Cells
por: O’Donnell, Edmond F., et al.
Publicado: (2012) -
The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor
por: O'Donnell, Edmond F., et al.
Publicado: (2010) -
The aryl hydrocarbon receptor mediates raloxifene-induced apoptosis in estrogen receptor-negative hepatoma and breast cancer cells
por: O'Donnell, E F, et al.
Publicado: (2014) -
Benzimidazoisoquinolines: A New Class of Rapidly Metabolized Aryl Hydrocarbon Receptor (AhR) Ligands that Induce AhR-Dependent Tregs and Prevent Murine Graft-Versus-Host Disease
por: Punj, Sumit, et al.
Publicado: (2014) -
Epigenetic Regulation of p21(cip1/waf1) in Human Cancer
por: Ocker, Matthias, et al.
Publicado: (2019)