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Peripheral kynurenine/tryptophan ratio is not a reliable marker of systemic indoleamine 2,3-dioxygenase: A lesson drawn from patients on hemodialysis

Indoleamine 2,3-dioxygenase (IDO) has emerged as a pivotal enzyme for mediating immune tolerance. Because IDO metabolizes tryptophan into kynurenine, the plasma kynurenine/tryptophan (Kyn/Trp) ratio has been widely used as a marker of systemic IDO. Here, we evaluated the clinical value of using the...

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Detalles Bibliográficos
Autores principales:	Chen, Yuanhan, Xie, Zhen, Xiao, Chenggen, Zhang, Min, Li, Zhilian, Xie, Jianteng, Zhang, Yusheng, Zhao, Xingchen, Zeng, Pengfei, Mo, Liyi, Liang, Xinling, Shi, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421927/ https://www.ncbi.nlm.nih.gov/pubmed/28445957 http://dx.doi.org/10.18632/oncotarget.15705

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