Lowered expression of microRNA-125a-5p in human hepatocellular carcinoma and up-regulation of its oncogenic targets sirtuin-7, matrix metalloproteinase-11, and c-Raf

Human microRNA-125a-5p (miR-125a) is expressed in most tissues where it downregulates the expression of membrane receptors or intracellular transductors of mitogenic signals, thus limiting cell proliferation. Expression of this miRNA generally increases with cell differentiation whereas it is downre...

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Detalles Bibliográficos
Autores principales: Coppola, Nicola, de Stefano, Giorgio, Panella, Marta, Onorato, Lorenzo, Iodice, Valentina, Minichini, Carmine, Mosca, Nicola, Desiato, Luisa, Farella, Nunzia, Starace, Mario, Liorre, Giulia, Potenza, Nicoletta, Sagnelli, Evangelista, Russo, Aniello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421930/
https://www.ncbi.nlm.nih.gov/pubmed/28445974
http://dx.doi.org/10.18632/oncotarget.15809

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