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Developing selective histone deacetylases (HDACs) inhibitors through ebselen and analogs

Histone deacetylases (HDACs) are key regulators of gene expression in cells and have been investigated as important therapeutic targets for cancer and other diseases. Different subtypes of HDACs appear to play disparate roles in the cells and are associated with specific diseases. Therefore, substan...

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Detalles Bibliográficos
Autores principales: Wang, Yuren, Wallach, Jason, Duane, Stephanie, Wang, Yuan, Wu, Jianghong, Wang, Jeffrey, Adejare, Adeboye, Ma, Haiching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422321/
https://www.ncbi.nlm.nih.gov/pubmed/28496307
http://dx.doi.org/10.2147/DDDT.S124977