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Thyroid Hormone Induces PGC-1α during Dendritic Outgrowth in Mouse Cerebellar Purkinje Cells
Thyroid hormone 3,3′,5-Triiodo-L-thyronine (T3) is essential for proper brain development. Perinatal loss of T3 causes severe growth defects in neurons and glia, including strong inhibition of dendrite formation in Purkinje cells in the cerebellar cortex. Here we show that T3 promotes dendritic outg...
Autores principales: | Hatsukano, Tetsu, Kurisu, Junko, Fukumitsu, Kansai, Fujishima, Kazuto, Kengaku, Mineko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422430/ https://www.ncbi.nlm.nih.gov/pubmed/28536504 http://dx.doi.org/10.3389/fncel.2017.00133 |
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