Horizontal gene transfer is not a hallmark of the human genome

Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as having the highest certainty of having been horizontally transferred, as well as 17 further genes from the 2001 human genome article,...

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Autor principal: Salzberg, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422933/
https://www.ncbi.nlm.nih.gov/pubmed/28482857
http://dx.doi.org/10.1186/s13059-017-1214-2
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author Salzberg, Steven L.
author_facet Salzberg, Steven L.
author_sort Salzberg, Steven L.
collection PubMed
description Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as having the highest certainty of having been horizontally transferred, as well as 17 further genes from the 2001 human genome article, and find little or no evidence to support claims of horizontal gene transfer (HGT). Please see related Research article: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0607-3 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-017-1214-2) contains supplementary material, which is available to authorized users.
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spelling pubmed-54229332017-05-12 Horizontal gene transfer is not a hallmark of the human genome Salzberg, Steven L. Genome Biol Correspondence Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as having the highest certainty of having been horizontally transferred, as well as 17 further genes from the 2001 human genome article, and find little or no evidence to support claims of horizontal gene transfer (HGT). Please see related Research article: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0607-3 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-017-1214-2) contains supplementary material, which is available to authorized users. BioMed Central 2017-05-08 /pmc/articles/PMC5422933/ /pubmed/28482857 http://dx.doi.org/10.1186/s13059-017-1214-2 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Correspondence
Salzberg, Steven L.
Horizontal gene transfer is not a hallmark of the human genome
title Horizontal gene transfer is not a hallmark of the human genome
title_full Horizontal gene transfer is not a hallmark of the human genome
title_fullStr Horizontal gene transfer is not a hallmark of the human genome
title_full_unstemmed Horizontal gene transfer is not a hallmark of the human genome
title_short Horizontal gene transfer is not a hallmark of the human genome
title_sort horizontal gene transfer is not a hallmark of the human genome
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422933/
https://www.ncbi.nlm.nih.gov/pubmed/28482857
http://dx.doi.org/10.1186/s13059-017-1214-2
work_keys_str_mv AT salzbergstevenl horizontalgenetransferisnotahallmarkofthehumangenome

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