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Adrenaline overdose in pediatric anaphylaxis: a case report

BACKGROUND: Adrenaline is the standard treatment for anaphylaxis but appropriate administration remains challenging, and iatrogenic overdose is easily overlooked. Despite the established importance of pediatric blood pressure measurement, its use remains inconsistent in clinical practice. CASE PRESE...

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Autores principales: Liew, Pui Yi Lily, Craven, John Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422946/
https://www.ncbi.nlm.nih.gov/pubmed/28482886
http://dx.doi.org/10.1186/s13256-017-1290-7
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author Liew, Pui Yi Lily
Craven, John Andrew
author_facet Liew, Pui Yi Lily
Craven, John Andrew
author_sort Liew, Pui Yi Lily
collection PubMed
description BACKGROUND: Adrenaline is the standard treatment for anaphylaxis but appropriate administration remains challenging, and iatrogenic overdose is easily overlooked. Despite the established importance of pediatric blood pressure measurement, its use remains inconsistent in clinical practice. CASE PRESENTATION: We report a case of adrenaline overdose in a 9-year-old white boy with anaphylaxis, where signs of adrenaline overdose were indistinguishable from progressive shock until blood pressure measurement was taken. CONCLUSIONS: The consequences of under-dosing adrenaline in anaphylaxis are well-recognized, but the converse is less so. Blood pressure measurement should be a routine part of pediatric assessment as it is key to differentiating adrenaline overdose from anaphylactic shock.
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spelling pubmed-54229462017-05-12 Adrenaline overdose in pediatric anaphylaxis: a case report Liew, Pui Yi Lily Craven, John Andrew J Med Case Rep Case Report BACKGROUND: Adrenaline is the standard treatment for anaphylaxis but appropriate administration remains challenging, and iatrogenic overdose is easily overlooked. Despite the established importance of pediatric blood pressure measurement, its use remains inconsistent in clinical practice. CASE PRESENTATION: We report a case of adrenaline overdose in a 9-year-old white boy with anaphylaxis, where signs of adrenaline overdose were indistinguishable from progressive shock until blood pressure measurement was taken. CONCLUSIONS: The consequences of under-dosing adrenaline in anaphylaxis are well-recognized, but the converse is less so. Blood pressure measurement should be a routine part of pediatric assessment as it is key to differentiating adrenaline overdose from anaphylactic shock. BioMed Central 2017-05-08 /pmc/articles/PMC5422946/ /pubmed/28482886 http://dx.doi.org/10.1186/s13256-017-1290-7 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Liew, Pui Yi Lily
Craven, John Andrew
Adrenaline overdose in pediatric anaphylaxis: a case report
title Adrenaline overdose in pediatric anaphylaxis: a case report
title_full Adrenaline overdose in pediatric anaphylaxis: a case report
title_fullStr Adrenaline overdose in pediatric anaphylaxis: a case report
title_full_unstemmed Adrenaline overdose in pediatric anaphylaxis: a case report
title_short Adrenaline overdose in pediatric anaphylaxis: a case report
title_sort adrenaline overdose in pediatric anaphylaxis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422946/
https://www.ncbi.nlm.nih.gov/pubmed/28482886
http://dx.doi.org/10.1186/s13256-017-1290-7
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