Heat shock factor 1 inhibits the mitochondrial apoptosis pathway by regulating second mitochondria-derived activator of caspase to promote pancreatic tumorigenesis

BACKGROUND: As a relatively conservative transcriptional regulator in biological evolution, heat shock factor 1 (HSF1) is activated by, and regulates the expression of heat shock proteins (HSPs) in response to a variety of stress conditions. HSF1 also plays a key role in regulating the development o...

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Detalles Bibliográficos
Autores principales: Liang, Wenjin, Liao, Yong, Zhang, Jing, Huang, Qi, Luo, Wei, Yu, Jidong, Gong, Jianhua, Zhou, Yi, Li, Xuan, Tang, Bo, He, Songqing, Yang, Jinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422968/
https://www.ncbi.nlm.nih.gov/pubmed/28482903
http://dx.doi.org/10.1186/s13046-017-0537-x

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