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Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart: Implications for Cardiac Reloading and Conditioning
This study sought to investigate the effects of mechanical unloading on myocardial energetics and the metabolic perturbation of heart failure (HF) in an effort to identify potential new therapeutic targets that could enhance the unloading-induced cardiac recovery. The authors prospectively examined...
Autores principales: | Diakos, Nikolaos A., Navankasattusas, Sutip, Abel, E. Dale, Rutter, Jared, McCreath, Lauren, Ferrin, Peter, McKellar, Stephen H., Miller, Dylan V., Park, Song Y., Richardson, Russell S., Deberardinis, Ralph, Cox, James E., Kfoury, Abdallah G., Selzman, Craig H., Stehlik, Josef, Fang, James C., Li, Dean Y., Drakos, Stavros G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422992/ https://www.ncbi.nlm.nih.gov/pubmed/28497127 http://dx.doi.org/10.1016/j.jacbts.2016.06.009 |
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