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BRAF inhibitor treatment of melanoma causing colonic polyps: An alternative hypothesis

Colonic polyps may arise from BRAF inhibitor treatment of melanoma, possibly due to paradoxical activation of the mitogen-activated protein (MAP)-kinase pathway. In an alternative evidence based scenario, tubular colonic adenomas with APC gene mutations have also been identified in the context of BR...

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Detalles Bibliográficos
Autores principales:	Kelleher, Fergal C, Callaghan, Grainne, Gallagher, Catriona, O’Sullivan, Hazel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2017
Materias:	Frontier
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423039/ https://www.ncbi.nlm.nih.gov/pubmed/28533659 http://dx.doi.org/10.3748/wjg.v23.i17.3022

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