Cargando…

Exosomes mediate hepatitis B virus (HBV) transmission and NK-cell dysfunction

Evidence suggests that exosomes can transfer genetic material between cells. However, their roles in hepatitis B virus (HBV) infection remain unclear. Here, we report that exosomes present in the sera of chronic hepatitis B (CHB) patients contained both HBV nucleic acids and HBV proteins, and transf...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yinli, Han, Qiuju, Hou, Zhaohua, Zhang, Cai, Tian, Zhigang, Zhang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423088/ https://www.ncbi.nlm.nih.gov/pubmed/27238466 http://dx.doi.org/10.1038/cmi.2016.24

Ejemplares similares

HBV suppresses expression of MICA/B on hepatoma cells through up-regulation of transcription factors GATA2 and GATA3 to escape from NK cell surveillance
por: Guan, Yun, et al.
Publicado: (2016)

The anti-HBV effect mediated by a novel recombinant eukaryotic expression vector for IFN-α
por: Yu, Haotian, et al.
Publicado: (2013)

Involvement of Activation of PKR in HBx-siRNA-Mediated Innate Immune Effects on HBV Inhibition
por: Han, Qiuju, et al.
Publicado: (2011)

Hepatitis B virus inhibits intrinsic RIG-I and RIG-G immune signaling via inducing miR146a
por: Hou, Zhaohua, et al.
Publicado: (2016)

Ectopic expression of microRNA-155 enhances innate antiviral immunity against HBV infection in human hepatoma cells
por: Su, Chenhe, et al.
Publicado: (2011)

Regulatory NK cells mediated between immunosuppressive monocytes and dysfunctional T cells in chronic HBV infection
por: Li, Haijun, et al.
Publicado: (2018)

NK Cell Dysfunction and Checkpoint Immunotherapy
por: Bi, Jiacheng, et al.
Publicado: (2019)

Exosomal HBV-DNA for diagnosis and treatment monitoring of chronic hepatitis B
por: Xu, Xu, et al.
Publicado: (2023)

Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Dual Infection
por: Liu, Zhihua, et al.
Publicado: (2006)

NKp30(+) NK cells are associated with HBV control during pegylated-interferon-alpha-2b therapy of chronic hepatitis B
por: Shen, Xiaokun, et al.
Publicado: (2016)

Intercellular transmission of Seneca Valley virus mediated by exosomes
por: Xu, Guowei, et al.
Publicado: (2020)

Prevention strategies of mother‐to‐child transmission of hepatitis B virus (HBV) infection
por: Hu, Yao, et al.
Publicado: (2020)

The Mechanisms of HBV-Induced Hepatocellular Carcinoma
por: Jiang, Yu, et al.
Publicado: (2021)

γδT Cells Suppress Liver Fibrosis via Strong Cytolysis and Enhanced NK Cell-Mediated Cytotoxicity Against Hepatic Stellate Cells
por: Liu, Meifang, et al.
Publicado: (2019)

Correction to: Intercellular transmission of Seneca Valley virus mediated by exosomes
por: Xu, Guowei, et al.
Publicado: (2020)

Development of Murine Hepatic NK Cells during Ontogeny: Comparison with Spleen NK Cells
por: Wu, Xian, et al.
Publicado: (2012)

Macrophages Help NK Cells to Attack Tumor Cells by Stimulatory NKG2D Ligand but Protect Themselves from NK Killing by Inhibitory Ligand Qa-1
por: Zhou, Zhixia, et al.
Publicado: (2012)

Association of preS/S Mutations with Occult Hepatitis B Virus (HBV) Infection in South Korea: Transmission Potential of Distinct Occult HBV Variants
por: Kim, Hong, et al.
Publicado: (2015)

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission
por: Alvarez-Erviti, Lydia, et al.
Publicado: (2011)

Horizontal Modes of Transmission of Hepatitis B Virus (HBV): A Systematic Review and Meta-Analysis
por: Sabeena, Sasidharanpillai, et al.
Publicado: (2022)

Semen-Derived Exosomes Mediate Immune Escape and Transmission of Reticuloendotheliosis Virus
por: Su, Qi, et al.
Publicado: (2021)

In situ analysis of hepatitis B virus (HBV) antigen and DNA in HBV-induced hepatocellular carcinoma
por: Zheng, Ye, et al.
Publicado: (2022)

Prospects for NK-based immunotherapy of chronic HBV infection
por: Jin, Xiaomeng, et al.
Publicado: (2022)

DeepHBV: a deep learning model to predict hepatitis B virus (HBV) integration sites
por: Wu, Canbiao, et al.
Publicado: (2021)

HBV Perinatal Transmission
por: Umar, Muhammad, et al.
Publicado: (2013)

Hepatitis Delta Virus: HDV-HBV Interactions
por: Sureau, Camille
Publicado: (2006)

Integrated HIV surveillance finds recent adult hepatitis B virus (HBV) transmission and intermediate HBV prevalence among military in uncharacterized Caribbean country
por: O’Connor, Siobhan M., et al.
Publicado: (2019)

Serum HBV pregenomic RNA exhibited opposite associations with NK(dim) and NK(bright) cell immunity in treatment-naïve chronic hepatitis B patients
por: Gu, Yurong, et al.
Publicado: (2021)

Molecular and Genetic Characterization of Hepatitis B Virus (HBV) among Saudi Chronically HBV-Infected Individuals
por: Di Stefano, Mariantonietta, et al.
Publicado: (2023)

Transmission of HBV DNA Mediated by Ceramide-Triggered Extracellular Vesicles
por: Sanada, Takahiro, et al.
Publicado: (2016)

RPB5-Mediating Protein Suppresses Hepatitis B Virus (HBV) Transcription and Replication by Counteracting the Transcriptional Activation of Hepatitis B virus X Protein in HBV Replication Mouse Model
por: Zhou, Qiaoling, et al.
Publicado: (2015)

Metabolic Regulation of Hepatitis B Virus Infection in HBV-Transgenic Mice
por: Lan, Wenning, et al.
Publicado: (2022)

CpG-C ODN M362 as an immunoadjuvant for HBV therapeutic vaccine reverses the systemic tolerance against HBV
por: Zhao, Huajun, et al.
Publicado: (2022)

New biomarkers of hepatitis B virus (HBV) infection: HBV RNA and HBV core-related antigen, new kids on the block?
por: Lim, Young-Suk
Publicado: (2023)

Toll-like receptor (TLR)-mediated innate immune responses in the control of hepatitis B virus (HBV) infection
por: Zhang, Ejuan, et al.
Publicado: (2014)

Roles of APOBEC3 in hepatitis B virus (HBV) infection and hepatocarcinogenesis
por: Zhang, Yuan, et al.
Publicado: (2021)

Seroprevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) among human immunodeficiency virus (HIV)-infected patients in an HBV endemic area in Brazil
por: da Silva, Claudinei Mesquita, et al.
Publicado: (2018)

Hepatitis B virus (HBV)-specific T-cell responses to recombinant HBV core protein in patients with normal liver function and co-infected with chronic HBV and human immunodeficiency virus 1 (HIV-1)
por: Zhang, Xin, et al.
Publicado: (2013)

The effectiveness of 20 μg hepatitis B vaccine used for the prevention of HBV vertical transmission
por: Yonghao, Guo, et al.
Publicado: (2022)

The Dual Role of Exosomes in Hepatitis A and C Virus Transmission and Viral Immune Activation
por: Longatti, Andrea
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_gdme1fqjf3mfe7k33cslktkv0r